BDBM8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1
SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO
InChI Key InChIKey=BSIZUMJRKYHEBR-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 8465
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human MMP8 (Phe21 to Gly467 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate...More data for this Ligand-Target Pair